MAP4K4-IN-44 |CAS:1623464-28-7 Probechem Biochemicals

Chemical Structure : MAP4K4-IN-44

MAP4K4-IN-44

Catalog No.: PC-62937Not For Human Use, Lab Use Only.

MAP4K4-IN-44 is a potent, moderately selective small molecule MAP4K4 inhibitor with IC50 of 5 nM in LC3K assay, demonstrates favorable in vivo bioavailability in mouse.

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Biological Activity

MAP4K4-IN-44 is a potent, moderately selective small molecule MAP4K4 inhibitor with IC50 of 5 nM in LC3K assay, demonstrates favorable in vivo bioavailability in mouse.

Physicochemical Properties

M.Wt	349.398
Formula	C18H19N7O
Appearance	Solid
CAS No.
Storage	Solide Powder -20 °C 12 Months; 4°C 6 Months	In Solvent -80 °C 6 Months; -20°C 6 Months
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Solubility	10 mM in DMSO
Chemical Name/SMILES	2-methyl-1-(4-(4-(pyridin-4-ylamino)pyrrolo[2,1-f][1,2,4]triazin-6-yl)-1H-pyrazol-1-yl)propan-2-ol

References

1. Wang L, et al. Bioorg Med Chem Lett. 2014 Sep 15;24(18):4546-4552.

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MAP4K4-IN-44

Biological Activity

Physicochemical Properties

References

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