Chemical Structure : MAX10181
CAS No.: 2171558-14-6
Catalog No.: PC-20279Not For Human Use, Lab Use Only.
MAX10181 (MAX-10181) is an orally active small molecule PD-L1 inhibitor, shows similar efficacy as Durvalumab in the head to head test of human PD-L1 knock-in MC38 cell line in human PD-1 knock-in mice.
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MAX10181 (MAX-10181) is an orally active small molecule PD-L1 inhibitor, shows similar efficacy as Durvalumab in the head to head test of human PD-L1 knock-in MC38 cell line in human PD-1 knock-in mice.
M.Wt | 527.54 | |
Formula | C29H28F3NO5 | |
Appearance | Solid | |
Storage |
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Solubility |
10 mM in DMSO |
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Chemical Name/SMILES |
(E)-2-((3-(3-(2,3-dihydrobenzo[b][1,4]dioxin-6-yl)-2-methylstyryl)-4-(trifluoromethyl)benzyl)amino)-3-hydroxy-2-methylpropanoic acid |
1. Yuguang Wang, et al. Cancer Res (2019) 79 (13_Supplement): LB-018.
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