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MB327

Chemical Structure : MB327

CAS No.: 61368-98-7

MB327

Catalog No.: PC-22398Not For Human Use, Lab Use Only.

MB327 is an antinicotinic bispyridinium compound, restores functional activity of nAChR. MB327 could restore soman-impaired neuromuscular function in vitro and improve survival of sarin, soman and tabun poisoned guinea pigs in vivo.

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

MB327 is an antinicotinic bispyridinium compound, restores functional activity of nAChR. MB327 could restore soman-impaired neuromuscular function in vitro and improve survival of sarin, soman and tabun poisoned guinea pigs in vivo.

Physicochemical Properties

M.Wt 566.31
Formula C21H32I2N2
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

1,1'-(propane-1,3-diyl)bis(4-(tert-butyl)pyridin-1-ium) iodide

References

1. Rappenglück S, et al. ChemMedChem. 2018 Sep 6;13(17):1806-1816.

2. Price ME, et al. Toxicol Lett. 2018 Sep 1;293:167-171.

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