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MBX1641

Chemical Structure : MBX1641

CAS No.: 329694-16-8

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MBX1641 (MBX-1641)

Catalog No.: PC-27561Not For Human Use, Lab Use Only.

MBX1641 (MBX-1641) is a small-molecule inhibitor of bacterial type III secretion (TTS, T3SS), not only bind effectively with YspD, but also bind to the functionally important domains of YspD and might lead to the functional inactivation of YspD, inhibits TIIISS effector protein ExoS in P. aeruginosa.

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

MBX1641 (MBX-1641) is a small-molecule inhibitor of bacterial type III secretion (TTS, T3SS), not only bind effectively with YspD, but also bind to the functionally important domains of YspD and might lead to the functional inactivation of YspD, inhibits TIIISS effector protein ExoS in P. aeruginosa.

Physicochemical Properties

M.Wt 368.21
Formula C17H15Cl2NO4
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

N-(benzo[d][1,3]dioxol-5-ylmethyl)-2-(2,4-dichlorophenoxy)propanamide

References

1. Duncan MC, et al. Antimicrob Agents Chemother. 2014;58(2):1118-26.

2. Aburto-Rodríguez NA, et al. Molecules. 2021 Dec 16;26(24):7635.

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