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MBX3132

Chemical Structure : MBX3132

CAS No.: 1636878-33-5

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MBX3132 (MBX 3132)

Catalog No.: PC-72797Not For Human Use, Lab Use Only.

MBX3132 is a small mocule inhibitor of AcrB multidrug efflux pump, fully potentiates the activity of a broad range of antibiotics at 0.1 uM.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

    Biological Activity

    MBX3132 is a small mocule inhibitor of AcrB multidrug efflux pump, fully potentiates the activity of a broad range of antibiotics at 0.1 uM.
    MBX3132 does not exhibit membrane-disrupting or antibacterial activity.

    Physicochemical Properties

    M.Wt 494.654
    Formula C27H34N4O3S
    Appearance Solid
    CAS No.
    Storage
    Solide Powder
    -20°C 12 Months; 4°C 6 Months
    In Solvent
    -80°C 6 Months; -20°C 6 Months
    Shipping
    Solubility

    10 mM in DMSO
    Chemical Name/SMILES

    N-(4-(2-((5-cyano-8-(2,6-dimethylmorpholino)-3,3-dimethyl-3,4-dihydro-1H-pyrano[3,4-c]pyridin-6-yl)thio)ethyl)phenyl)acetamide

    References

    1. Hanno Sjuts, et al. Proc Natl Acad Sci U S A. 2016 Mar 29; 113(13): 3509–3514.

    2. Coline Plé, et al. Nat Commun. 2022 Jan 10;13(1):115.

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