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Chemical Structure : MC-100093
Catalog No.: PC-72279Not For Human Use, Lab Use Only.
MC-100093 (MC100093) is a potent, orally bioavailable upregulator of glutamate transporter-1 (GLT-1) and devoid of antimicrobial properties.
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MC-100093 (MC100093) is a potent, orally bioavailable upregulator of glutamate transporter-1 (GLT-1) and devoid of antimicrobial properties.
MC-100093 enhanced uptake of glutamate into astrocytes in a mouse neuron/astrocyte co-culture model with IC50 of 0.1 uM.
MC-100093 restored the expression of NA core GLT-1.
MC-100093 (50 mg/kg) attenuated cue-primed relapse to cocaine-seeking without reducing motivation to consume regular chow or sucrose pellets or affecting body weight.
| M.Wt | 269.345 | |
| Formula | C13H23N3O3 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Lori A Knackstedt, et al. J Pharmacol Exp Ther. 2021 Aug;378(2):51-59.
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