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Chemical Structure : MCT1-IN-4a
Catalog No.: PC-62725Not For Human Use, Lab Use Only.
MCT1-IN-4a is a potent, selective monocarboxylate transporter 1 (MCT1) inhibitor with IC50 of 90 nM.
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MCT1-IN-4a is a potent, selective monocarboxylate transporter 1 (MCT1) inhibitor with IC50 of 90 nM; exhibits significant single agent activity in MCT1 expressing GL261-luc2 syngraft model, but not in MCT4 expressing MDA-MB-231 xenograft model; has good absorption, metabolic stability, and a low drug efflux ratio.
| M.Wt | 385.419 | |
| Formula | C24H19NO4 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Gurrapu S, et al. Bioorg Med Chem Lett. 2016 Jul 15;26(14):3282-6.
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