Welcome to ProbeChem!Global Supplier of Chemical Probes, Inhibitors & Agonists.
EN | CN

Product Inquiry: sales@probechem.com
Order/PO receiving: order@probechem.com

You are here:Home-Chemical Inhibitors & Agonists-Membrane Transporter/Ion Channel-Monocarboxylate Transporter (MCT)-MCT4 inhibitor CB-2
MCT4 inhibitor CB-2

Chemical Structure : MCT4 inhibitor CB-2

CAS No.: 331840-43-8

Add to Favorites

MCT4 inhibitor CB-2 (CB-2)

Catalog No.: PC-49038Not For Human Use, Lab Use Only.

MCT4 inhibitor CB-2 is a novel small molecule MCT4 inhibitor with significantly inhibitory effect on lactate secretion and striking cytotoxic activity against MDA‐MB‐231 cells.

Packing Price Stock Quantity
50 mg Get quote
100 mg Get quote
250 mg Get quote
Get Quotation Now
* Please select Quantity before adding items.
 or Bulk Inquiry

Bulk size, bulk discount!

E-mail: sales@probechem.com

Tech Support: tech@probechem.com

Purity & Documentation Purity: >98% (HPLC) Select Batch:

    Biological Activity

    MCT4 inhibitor CB-2 is a novel small molecule MCT4 inhibitor with significantly inhibitory effect on lactate secretion and striking cytotoxic activity against MDA‐MB‐231 cells.
    CB‐2 shows anti‐tumor effects against human cancer cell MDA‐MB‐231‐driven xenograft tumors in nude mice.
    A triple combination of metformin, trabectedin, and CB‐2 strongly inhibits the growth of breast cancer cells, inhibits HG‐induced breast cancer progression in vivo.

    Physicochemical Properties

    M.Wt 608.313
    Formula C30H21BrCl2N2O3
    Appearance Solid
    CAS No.
    Storage
    Solide Powder
    -20°C 12 Months; 4°C 6 Months
    In Solvent
    -80°C 6 Months; -20°C 6 Months
    Shipping
    Solubility

    10 mM in DMSO
    Chemical Name/SMILES

    (E)-2-(1-(2-(4-bromophenoxy)ethyl)-1H-benzo[d]imidazol-2-yl)-1-(2-chlorophenyl)vinyl 2-chlorobenzoate

    References

    1. Qiongyu Hao, et al. Adv Sci (Weinh). 2022 Feb;9(6):e2102303.

    Copyright © 2022 probechem.com. All Rights Reserved. probechem Copyright

    Contact Us sales@probechem.com

    Bulk Inquiry

    * Indicates a Required FieldYour information is safe with us.

    • *Product name:
    • *Applicant name:
    • *Email address:
    • *Organization name:
    • *Requested quantity:
    • *Country:
    • *Additional Information:

    Get Quote

    * Indicates a Required FieldYour information is safe with us.

    • *Product name:
    • *Applicant name:
    • *Email address:
    • *Organization name:
    • *Requested quantity:
    • *Country:
    • Additional Information: