MF266-3 | EP3 antagonist | Probechem Biochemicals

Chemical Structure : MF266-3

MF266-3 (MF 266-3)

Catalog No.: PC-63011Not For Human Use, Lab Use Only.

MF266-3 is a potent, selective prostaglandin E receptor subtype 3 (EP3) antagonist with Ki of 0.8 nM.

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Biological Activity

MF266-3 is a potent, selective prostaglandin E receptor subtype 3 (EP3) antagonist with Ki of 0.8 nM.
MF266-3 displayes a relatively good selectivity over other prostanoid receptors.

Physicochemical Properties

M.Wt	570.882
Formula	C27H21BrClNO4S
Appearance	Solid
CAS No.
Storage	Solide Powder -20 °C 12 Months; 4°C 6 Months	In Solvent -80 °C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	(2E)-N-[(5-bromo-2-methoxyphenyl)sulfonyl]-3-[5-chloro-2-(2-naphthylmethyl)phenyl]acrylamide

References

1. Clark P. et al. J Pharmacol Exp Ther. 2008 May;325(2):425-34.

2. Juteau H, et al. Bioorg Med Chem. 2001 Aug;9(8):1977-84.

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MF266-3 (MF 266-3)

Biological Activity

Physicochemical Properties

References

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