Welcome to ProbeChem!Global Supplier of Chemical Probes, Inhibitors & Agonists.
    English |     Chinese

Product Inquiry: sales@probechem.com
Order/PO receiving: order@probechem.com

You are here:Home-Chemical Inhibitors & Agonists-GPCR-Prostaglandin Receptor-MF498
MF498

Chemical Structure : MF498

CAS No.: 915191-42-3

Add to Favorites

MF498 (MF-498)

Catalog No.: PC-42699Not For Human Use, Lab Use Only.

MF498 is a selective prostaglandin E receptor subtype 4 (EP4) antagonist with Ki of 0.74 nM.

Packing Price Stock Quantity
10 mg $158 In stock
25 mg $278 In stock
50 mg Get quote
100 mg Get quote
Get Quotation Now
* Please select Quantity before adding items.
 or Bulk Inquiry

Bulk size, bulk discount!

E-mail: sales@probechem.com

Tech Support: tech@probechem.com

Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

MF498 is a selective prostaglandin E receptor subtype 4 (EP4) antagonist with Ki of 0.74 nM.
MF498 inhibits PGE2-induced cAMP accumulation in HEK293 cells stably expressing human EP4 receptor with IC50 of 1.7 nM.
MF498 inhibits inflammation in adjuvant-induced arthritis (AIA) model.

Physicochemical Properties

M.Wt 603.6853
Formula C32H33N3O7S
Appearance Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility

DMSO: ≥ 31 mg/mL
Chemical Name/SMILES

Benzeneacetamide, N-[[[4-(5,9-diethoxy-6,8-dihydro-6-oxo-7H-pyrrolo[3,4-g]quinolin-7-yl)-3-methylphenyl]methyl]sulfonyl]-2-methoxy-

References

1. Clark P. et al. J Pharmacol Exp Ther. 2008 May;325(2):425-34.

2. Burch JD, et al. Bioorg Med Chem Lett. 2008 Mar 15;18(6):2048-54.

Copyright © 2022 probechem.com. All Rights Reserved. probechem Copyright

Contact Us sales@probechem.com

Bulk Inquiry

* Indicates a Required FieldYour information is safe with us.

  • *Product name:
  • *Applicant name:
  • *Email address:
  • *Organization name:
  • *Requested quantity:
  • *Country:
  • *Additional Information:

Get Quote

* Indicates a Required FieldYour information is safe with us.

  • *Product name:
  • *Applicant name:
  • *Email address:
  • *Organization name:
  • *Requested quantity:
  • *Country:
  • Additional Information: