Catalog No.: PC-45577Not For Human Use, Lab Use Only.
MG-101 (ALLN) is a potent inhibitor of cysteine proteases including calpain I (Ki= 190 nM), calpain II (Ki= 220 nM), cathepsin B (Ki= 150 nM) and cathepsin L (Ki= 500 pM).
MG-101 (ALLN) is a potent inhibitor of cysteine proteases including calpain I (Ki= 190 nM), calpain II (Ki= 220 nM), cathepsin B (Ki= 150 nM) and cathepsin L (Ki= 500 pM).
MG-101 activates p53-dependent apoptosis in tumor cell lines.
MG-101 increases activated p53, p21 and caspase levels and promotes cell cycle arrest through inhibition of cyclin D degradation in vitro.
