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MGV354 R-form

Chemical Structure : MGV354 R-form

CAS No.: 1852495-87-4

MGV354 R-form (MGV 354;MGV-354)

Catalog No.: PC-35120Not For Human Use, Lab Use Only.

MGV354 is a novel potent, selective soluble Guanylate Cyclase (sGC) activator, lowers intraocular pressure (IOP) in preclinical models of glaucoma..

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

MGV354 is a novel potent, selective soluble Guanylate Cyclase (sGC) activator, lowers intraocular pressure (IOP) in preclinical models of glaucoma.

Physicochemical Properties

M.Wt 575.713
Formula C35H37N5O3
Appearance Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

(R)-1-(6-(3-((4-(1-(cyclopropanecarbonyl)piperidin-4-yl)-2-methylphenyl)amino)-2,3-dihydro-1H-inden-4-yl)pyridin-2-yl)-5-methyl-1H-pyrazole-4-carboxylic acid

References

1. Prasanna G, et al. Invest Ophthalmol Vis Sci. 2018 Apr 1;59(5):1704-1716.

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