MIN-101 |CAS:359625-79-9 Probechem Biochemicals

Chemical Structure : MIN-101

CAS No.: 359625-79-9

MIN-101 (Roluperidone;CYR-101;MT-210;MIN101)

Catalog No.: PC-61105Not For Human Use, Lab Use Only.

MIN-101 (Roluperidone, CYR-101, MT-210) is a higly potent 5-HT2A and sigma 2 receptor antagonist, with no direct dopamine affinities, for treatment of negative symptoms in schizophrenia..

Packing	Price	Stock
5 mg	$118	In stock
10 mg	$188	In stock
25 mg	$328	In stock
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Biological Activity

MIN-101 (Roluperidone, CYR-101, MT-210) is a higly potent 5-HT2A and sigma 2 receptor antagonist with Ki of 7.53 nM and 8.19 nM respectively.
MIN-101 (Roluperidone, CYR-101, MT-210) shows with no direct dopamine affinities, for treatment of negative symptoms in schizophrenia.

Physicochemical Properties

M.Wt	366.429
Formula	C22H23F2N2O2
Appearance	Solid
CAS No.
Storage	Solide Powder -20 °C 12 Months; 4°C 6 Months	In Solvent -80 °C 6 Months; -20°C 6 Months
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Solubility	10 mM in DMSO
Chemical Name/SMILES	2-[[1-[2-(4-Fluorophenyl)-2-oxoethyl]-4-piperidinyl]methyl]-2,3-dihydro-1H-isoindol-1-one

References

1. Davidson M, et al. Am J Psychiatry. 2017 Dec 1;174(12):1195-1202.

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MIN-101 (Roluperidone;CYR-101;MT-210;MIN101)

Biological Activity

Physicochemical Properties

References

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