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MIPS-19417

Chemical Structure : MIPS-19417

CAS No.: 2001083-66-3

MIPS-19417 (MIPS19417)

Catalog No.: PC-25114Not For Human Use, Lab Use Only.

MIPS-19417 is a potent, selective PI3KC2β inhibitor with IC50 of 278 nM, does not inhibit PI3KC2α (IC50>10 uM).

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

MIPS-19417 is a potent, selective PI3KC2β inhibitor with IC50 of 278 nM, does not inhibit PI3KC2α (IC50>10 uM).

Physicochemical Properties

M.Wt 527.58
Formula C25H31F2N9O2
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

(R)-(4-(4-(2-(difluoromethyl)-1H-benzo[d]imidazol-1-yl)-6-morpholino-1,3,5-triazin-2-yl)piperazin-1-yl)(piperidin-2-yl)methanone

References

1. Maria V Selvadurai, et al. Sci Transl Med. 2020 Jul 22;12(553):eaar8430.

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