MIPS-21335 | PI3KC2α inhibitor | Probechem Biochemicals

Chemical Structure : MIPS-21335

MIPS-21335 (MIPS21335)

Catalog No.: PC-23004Not For Human Use, Lab Use Only.

MIPS-19416 is a potent selective inhibitor of class II alpha PI3K (PI3K-C2α) with IC50 of 7 nM, six-fold selective over PI3K-C2β, 20-fold over PI3K-p110α.

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Biological Activity

MIPS-19416 is a potent selective inhibitor of class II alpha PI3K (PI3K-C2α) with IC50 of 7 nM, six-fold selective over PI3K-C2β, 20-fold over PI3K-p110α.

Physicochemical Properties

M.Wt	487.48
Formula	C24H21N7O5
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
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Solubility	10 mM in DMSO
Chemical Name/SMILES	6-Amino-N-[2,3-dihydro-7-methoxy-8-[(3-nitrophenyl)methoxy]imidazo[1,2-c]quinazolin-5-yl]-3-pyridinecarboxamide

References

1. Maria V Selvadurai, et al. Sci Transl Med. 2020 Jul 22;12(553):eaar8430.

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MIPS-21335 (MIPS21335)

Biological Activity

Physicochemical Properties

References

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