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Chemical Structure : MJM-1
Catalog No.: PC-72875Not For Human Use, Lab Use Only.
MJM-1 is a small-molecule brain-penetrant HDAC inhibitor that increases the overall level of histone 3 (H3) acetylation in prostate cancer cell line.
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MJM-1 is a small-molecule brain-penetrant HDAC inhibitor that increases the overall level of histone 3 (H3) acetylation in prostate cancer cell line.
MJM-1 injected intraperitoneally (i.p.) crossed the BBB in mice and could be detected in the hippocampus, a brain region that mediates memory.
MJM-1 (post-training i.p. administration) enhanced hippocampus-dependent spatial memory consolidation in male mice.
| M.Wt | 462.66 | |
| Formula | C22H38O6S2 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Jawad B Belayet, et al. J Med Chem. 2022 Feb 24;65(4):3388-3403.
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