Catalog No.: PC-60405Not For Human Use, Lab Use Only.
MK-0536 is a potent HIV-1 integrase strand transfer inhibitor with IC50 of 33 nM, 9.5 nM, 40 nM, 20 nM and 237 nM for wt IN, IN Y143R, IN N155H, G118R and IN G140S-Q148H, respectively.
MK-0536 is a potent HIV-1 integrase strand transfer inhibitor with IC50 of 33 nM, 9.5 nM, 40 nM, 20 nM and 237 nM for wt IN, IN Y143R, IN N155H, G118R and IN G140S-Q148H, respectively.
MK-0536 shows antiviral activities against RAL-resistant viruses with IC50 of 17/6.0/15/20/77 nM in the cell-based assay for WT, IN Y143R, IN N155H, G118R and IN G140S-Q148H viruses.
