MK-0736 | 11β-HSD1 inhibitor | Probechem Biochemicals

Chemical Structure : MK-0736

MK-0736 (MK0736)

Catalog No.: PC-21934Not For Human Use, Lab Use Only.

MK-0736 is a potent, selective 11β-hydroxysteroid dehydrogenase type 1 (11β-HSD1) inhibitor, shows favourable effect on glucose and lipid metabolism, weight reduction and adipokine levels.

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Biological Activity

MK-0736 is a potent, selective 11β-hydroxysteroid dehydrogenase type 1 (11β-HSD1) inhibitor, shows favourable effect on glucose and lipid metabolism, weight reduction and adipokine levels.

Physicochemical Properties

M.Wt	469.57
Formula	C23H30F3N3O2S
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
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Solubility	10 mM in DMSO
Chemical Name/SMILES	3-(4-(3-(Ethylsulfonyl)propyl)bicyclo[2.2.2]octan-1-yl)-4-methyl-5-(2-(trifluoromethyl)phenyl)-4H-1,2,4-triazole

References

1. Shah S, et al. J Am Soc Hypertens. 2011 May-Jun;5(3):166-76.

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MK-0736 (MK0736)

Biological Activity

Physicochemical Properties

References

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