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Chemical Structure : MK-0752
CAS No.: 471905-41-6
Catalog No.: PC-42758Not For Human Use, Lab Use Only.
MK-0752 (MK0752) is a potent γ-secretase inhibitor that shows dose-dependent reduction of Aβ40 with an IC50 of 5 nM in human SH-SY5Y cells, inhibits Notch signaling.
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 5 mg | $128 | In stock | |
| 10 mg | $188 | In stock | |
| 25 mg | $288 | In stock | |
| 100 mg | Get quote |
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MK-0752 (MK0752) is a potent γ-secretase inhibitor that shows dose-dependent reduction of Aβ40 with an IC50 of 5 nM in human SH-SY5Y cells, inhibits Notch signaling.
| M.Wt | 442.9038 | |
| Formula | C21H21ClF2O4S | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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| Chemical Name/SMILES |
Cyclohexanepropanoic acid, 4-[(4-chlorophenyl)sulfonyl]-4-(2,5-difluorophenyl)-, cis- |
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1. Cook JJ, et al. J Neurosci. 2010 May 12;30(19):6743-50.
2. Previs RA, et al. Clin Cancer Res. 2015 Mar 1;21(5):955-61.
3. Brana I, et al. Br J Cancer. 2014 Nov 11;111(10):1932-44.
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