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MK-0773

Chemical Structure : MK-0773

CAS No.: 606101-58-0

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MK-0773 (MK0773;MK 0773;PF 05314882;PF-05314882;PF05314882)

Catalog No.: PC-42794Not For Human Use, Lab Use Only.

MK-0773 (PF-05314882) is a potent, selective androgen receptor modulator (SARM) with binding IC50 of 6.6 nM.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

MK-0773 (PF-05314882) is a potent, selective androgen receptor modulator (SARM) with binding IC50 of 6.6 nM.
MK-0773 (PF-05314882) displays no binding to other nuclear receptors ( GR, IC50> 2 uM) and 5α-reductase (IC50>10 uM).
MK-0773 (PF-05314882) improves muscle function while minimizing effects on other tissues.

Physicochemical Properties

M.Wt 479.5896
Formula C27H34FN5O2
Appearance Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

1H-Indeno[5,4-f]quinoline-7-carboxamide, 3-fluoro-2,4a,4b,5,6,6a,7,8,9,9a,9b,10,11,11a-tetradecahydro-N-(3H-imidazo[4,5-b]pyridin-2-ylmethyl)-1,4a,6a-trimethyl-2-oxo-, (4aS,4bS,6aS,7S,9aS,9bS,11aR)-

References

1. Schmidt A, et al. J Biol Chem. 2010 May 28;285(22):17054-64.

2. Papanicolaou DA, et al. J Nutr Health Aging. 2013;17(6):533-43.

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