MK-0916 | 11β-HSD1 inhibitor | Probechem Biochemicals

Chemical Structure : MK-0916

Catalog No.: PC-27069Not For Human Use, Lab Use Only.

MK-0916 is a potent, selective 11β-hydroxysteroid dehydrogenase 1 (11β-HSD1) inhibitor with IC50 of 0.03 uM.

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Biological Activity

MK-0916 is a potent, selective 11β-hydroxysteroid dehydrogenase 1 (11β-HSD1) inhibitor with IC50 of 0.03 uM.

M.Wt	331.82
Formula	C18H19ClFN3
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	3-(trans-(1r,3r)-1-(4-Chlorophenyl)-3-fluorocyclobutyl)-4,5-dicyclopropyl-4H-1,2,4-triazole

1. Shah S, et al. J Am Soc Hypertens. 2011 May-Jun;5(3):166-76.

2. Harno E, et al. Endocrinology. 2013 Dec;154(12):4580-93.