MK-1454 (Ulevostinag) | STING agonist | Probechem Biochemicals

Chemical Structure : MK-1454

Catalog No.: PC-72369Not For Human Use, Lab Use Only.

MK-1454 (Ulevostinag) is a novel cyclic dinucleotide STING agonist with robust tumor cytokine upregulation and effective antitumor activity.

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Biological Activity

MK-1454 (Ulevostinag) is a novel cyclic dinucleotide STING agonist with robust tumor cytokine upregulation and effective antitumor activity.

M.Wt	710.521
Formula	C20H22F2N10O9P2S2
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	(2R,5R,7R,8S,10R,12aR,14R,15S,15aR,16R)-7- (2-amino-6-oxo-1,6-dihydro-9H-purin-9-yl)-14-(6-amino-9Hpurin- 9-yl)-15,16-difluoro-2,10-bis(sulfanyl)octahydro- 2H,10H,12H-2λ5,10λ5-5,8-methanofuro[3,2-l][1,3,6,9,11,2,10]- pentaoxadiphosphacyclotetradecine-2,10-dione

1. Chang W, et al. J Med Chem. 2022 Apr 14;65(7):5675-5689.