MK-1597 | Renin inhibitor | Probechem Biochemicals

Chemical Structure : MK-1597

Catalog No.: PC-27070Not For Human Use, Lab Use Only.

MK-1597 (ACT-178882) is a potent, direct renin inhibitor with IC50 of 1.4 nM, demonstrates blood pressure lowering properties.

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Biological Activity

MK-1597 (ACT-178882) is a potent, direct renin inhibitor with IC50 of 1.4 nM, demonstrates blood pressure lowering properties.

M.Wt	647.03
Formula	C33H38Cl3N3O4
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	(3R,4S)-N-(2-Chloro-5-(2-methoxyethyl)benzyl)-N-cyclopropyl-4-(6-(2-(2,6-dichloro-4-methylphenoxy)ethoxy)pyridin-3-yl)piperidine-3-carboxamide

1. Corminboeuf O, et al. Bioorg Med Chem Lett. 2010 Nov 1;20(21):6291-6.