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Chemical Structure : MK-3577
Catalog No.: PC-70055Not For Human Use, Lab Use Only.
A potent, oral active glucagon receptor antagonist blocking the glucagon effect for the treatment of T2DM.
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A potent, oral active glucagon receptor antagonist blocking the glucagon effect for the treatment of T2DM; inhibits glucagon-mediated cAMP increases in CHO cells expressing the human glucagon receptor with IC50 of 8.3 nM.
Diabetes
Phase 2 Discontinued
| M.Wt | 521.03 | |
| Formula | C30H30ClFN2O3 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Peng JZ, et al. AAPS J. 2014 Nov;16(6):1259-70.
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