Welcome to ProbeChem!Global Supplier of Chemical Probes, Inhibitors & Agonists.
Chemical Structure : MK-4166
CAS No.:
Catalog No.: PC-Ab1069Not For Human Use, Lab Use Only.
MK-4166 is a humanized IgG1 agonist monoclonal antibody targeting GITR. MK-4166 decreased induction and suppressive effects of T regs in vitro In human TIL cultures, MK-4166 induced phosphorylation of NFκB and increased expression of dual specificity phosphatase 6 (DUSP6), indicating that MK-4166 activated downstream NFκB and Erk signaling pathways..
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 1 mg | $358 | In stock | |
| 5 mg | $758 | In stock | |
| 10 mg | $1280 | In stock | |
| 100 mg | Get quote |
Bulk size, bulk discount!
E-mail: sales@probechem.com
Tech Support: tech@probechem.com
MK-4166 is a humanized IgG1 agonist monoclonal antibody targeting GITR. MK-4166 decreased induction and suppressive effects of T regs in vitro In human TIL cultures, MK-4166 induced phosphorylation of NFκB and increased expression of dual specificity phosphatase 6 (DUSP6), indicating that MK-4166 activated downstream NFκB and Erk signaling pathways.
| M.Wt | ||
| Formula | Human IgG1-Kappa | |
| Appearance | Solid | |
| Storage |
|
|
| Solubility |
PBS, pH 7.0 Contains no stabilizers or preservatives |
|
| Chemical Name/SMILES |
|
|
Copyright © 2022 probechem.com. All Rights Reserved. probechem Copyright
