Chemical Structure : MK-571
CAS No.:
115104-28-4
MK-571
(L-660711, MK571)
Catalog No. : PC-26199Not For Human Use, Lab Use Only.
MK-571 (L-660711) is a potent and specific LTD4 receptor antagonist with Ki of 0.22 nM, also inhibits MRP4 (ABCC4) and ABCC1 (MRP1).
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Purity & Documentation Purity:
>98% (HPLC) Select Batch: PC-2619901
Biological Activity
MK-571 (L-660711) is a potent and specific LTD4 receptor antagonist with Ki of 0.22 nM, also inhibits MRP4 (ABCC4) and ABCC1 (MRP1).
Physicochemical Properties
M.Wt
515.08
Formula
C26H27ClN2O3S2
Appearance
Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility
10 mM in DMSO
Chemical Name/SMILES
(E)-3-(((3-(2-(7-Chloroquinolin-2-yl)vinyl)phenyl)((3-(dimethylamino)-3-oxopropyl)thio)methyl)thio)propanoic acid
References
1. Gauthier JY, et al. J Med Chem. 1990 Oct;33(10):2841-5.
2. Vellenga E, et al. Br J Pharmacol. 1999 May;127(2):441-8.
3. Lynch K, et al. Nature. 1999 Jun 24;399(6738):789-93.
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