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MK-7288

Chemical Structure : MK-7288

CAS No.: 936626-07-2

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MK-7288 (MK7288, MK 7288)

Catalog No.: PC-61337Not For Human Use, Lab Use Only.

MK-7288 is a selective histamine H3 receptor inverse agonist for the treatment of sleep apnoea syndrome.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

    Biological Activity

    MK-7288 is a selective histamine H3 receptor inverse agonist for the treatment of sleep apnoea syndrome.
    MK-7288 significantly prolongs MWT sleep latency, and improves car driving simulation standard deviation of lane position in clinical trials.

    Physicochemical Properties

    M.Wt 401.507
    Formula C22H31N3O4
    Appearance Solid
    CAS No.
    Storage
    Solide Powder
    -20 °C 12 Months; 4°C 6 Months
    In Solvent
    -80 °C 6 Months; -20°C 6 Months
    Shipping
    Solubility

    10 mM in DMSO
    Chemical Name/SMILES

    (1r,4r)-2'-methoxy-N-methyl-7'-oxo-N-(2-(piperidin-1-yl)ethyl)-7'H-spiro[cyclohexane-1,5'-furo[3,4-b]pyridine]-4-carboxamide

    References

    1. Sun H, et al. J Clin Pharmacol. 2013 Dec;53(12):1294-302.

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