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MK-7622

Chemical Structure : MK-7622

CAS No.: 1227923-29-6

MK-7622 (MK7622)

Catalog No.: PC-22975Not For Human Use, Lab Use Only.

MK-7622 is a potent, selective and CNS penetrant M1 muscarinic receptor positive allosteric modulator (PAM).

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10 mg $88 In stock
25 mg $138 In stock
50 mg $228 In stock
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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

MK-7622 is a potent, selective and CNS penetrant M1 muscarinic receptor positive allosteric modulator (PAM).
MK-7622 attenuated the cognitive-impairing effects of the muscarinic receptor antagonist scopolamine and altered quantitative electroencephalography (qEEG) in both rhesus macaque and human.

Physicochemical Properties

M.Wt 399.49
Formula C25H25N3O2
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

3-[(1S,2S)-2-Hydroxycyclohexyl]-6-[(6-methyl-3-pyridinyl)methyl]benzo[h]quinazolin-4(3H)-one

References

1. Uslaner JM, et al. J Pharmacol Exp Ther. 2018 Jun;365(3):556-566.

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