Chemical Structure : MK-7622
CAS No.: 1227923-29-6
Catalog No.: PC-22975Not For Human Use, Lab Use Only.
MK-7622 is a potent, selective and CNS penetrant M1 muscarinic receptor positive allosteric modulator (PAM).
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MK-7622 is a potent, selective and CNS penetrant M1 muscarinic receptor positive allosteric modulator (PAM).
MK-7622 attenuated the cognitive-impairing effects of the muscarinic receptor antagonist scopolamine and altered quantitative electroencephalography (qEEG) in both rhesus macaque and human.
M.Wt | 399.49 | |
Formula | C25H25N3O2 | |
Appearance | Solid | |
Storage |
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Solubility |
10 mM in DMSO |
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Chemical Name/SMILES |
3-[(1S,2S)-2-Hydroxycyclohexyl]-6-[(6-methyl-3-pyridinyl)methyl]benzo[h]quinazolin-4(3H)-one |
1. Uslaner JM, et al. J Pharmacol Exp Ther. 2018 Jun;365(3):556-566.
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