Chemical Structure : MK-886
CAS No.:
118414-82-7
MK-886
(L-663,536, MK886, L 663536)
Catalog No. : PC-20006Not For Human Use, Lab Use Only.
MK-886 (L-663,536) is a potent, selective and orally active inhibitor of 5-lipoxygenase-activating protein (FLAP) with IC50 of 30 nM.
Packing Price Stock Quantity 10 mg $98 In stock 0 1 2 3 4 5 25 mg $168 In stock 0 1 2 3 4 5 50 mg $268 In stock 0 1 2 3 4 5 100 mg $458 In stock 0 1 2 3 4 5 250 mg Get quote 0 1 2 3 4 5
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Purity & Documentation Purity:
>98% (HPLC) Select Batch: PC-2000601
Biological Activity
MK-886 (L-663,536) is a potent, selective and orally active inhibitor of 5-lipoxygenase-activating protein (FLAP ) with IC50 of 30 nM.
Physicochemical Properties
M.Wt
472.08
Formula
C27H34ClNO2S
Appearance
Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility
10 mM in DMSO
Chemical Name/SMILES
1-[(4-chlorophenyl)methyl]-3-[(1,1-dimethylethyl)thio]-alpha,alpha-dimethyl-5-(1-methylethyl)-1H-indole-2-propanoic acid
References
1. Guhlmann A, et al. J Exp Med.
2. Gillard J, et al. Can J Physiol Pharmacol
3. Dixon RA, et al. Nature.
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