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You are here:Home-Chemical Inhibitors & Agonists-Membrane Transporter/Ion Channel-Calcium Channel -MK-8998
MK-8998

Chemical Structure : MK-8998

CAS No.: 953778-58-0

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MK-8998 (Suvecaltamide, CX-8998, MK8998)

Catalog No.: PC-42314Not For Human Use, Lab Use Only.

MK-8998 (Suvecaltamide, CX-8998) is a potent and selective antagonist of the T-type calcium channel for the treatment of schizophrenia.

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5 mg $138 In stock
10 mg $218 In stock
25 mg $368 In stock
50 mg $558 In stock
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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

MK-8998 (Suvecaltamide, CX-8998) is a potent and selective antagonist of the T-type calcium channel for the treatment of schizophrenia.
MK-8998 does not block D2, 5HT2a, muscarinic, or histaminic receptors.
MK-8998 has the potential for a substantially improved side effect profile compared with currently available atypical antipsychotics.

Physicochemical Properties

M.Wt 380.4040296
Formula C20H23F3N2O2
Appearance Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

Benzeneacetamide, 4-(1-methylethyl)-N-[(1R)-1-[5-(2,2,2-trifluoroethoxy)-2-pyridinyl]ethyl]-

References

1. Egan MF, et al. Hum Psychopharmacol. 2013 Mar;28(2):124-33.

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