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Chemical Structure : ML-184
CAS No.: 794572-10-4
Catalog No.: PC-70188Not For Human Use, Lab Use Only.
ML-184 (ML184) is a potent, selective GPR55 agonist with EC50 of 263 nM, >120-fold, 83-fold, and 57-fold selectivity against GPR35, CB1 and CB2.
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|---|---|---|---|
| 5 mg | $248 | In stock | |
| 10 mg | $388 | In stock | |
| 25 mg | $588 | In stock | |
| 100 mg | Get quote |
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ML-184 (ML184) is a potent, selective GPR55 agonist with EC50 of 263 nM, >120-fold, 83-fold, and 57-fold selectivity against GPR35, CB1 and CB2.
ML-184 shows activity in activating the downstream responses of ERK phosphorylation and PKC β II translocation.
| M.Wt | 470.6 | |
| Formula | C25H34N4O3S | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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| Chemical Name/SMILES |
3-[[4-(2,3-Dimethylphenyl)-1-piperazinyl]carbonyl]-N,N-dimethyl-4-(1-pyrrolidinyl)benzenesulfonamide |
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1. Heynen-Genel S, et al. Probe Reports from the NIH Molecular Libraries Program [Internet].
2. Lingerfelt MA, et al. Biochemistry. 2017 Jan 24;56(3):473-486.
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