ML175 | GSTO1 inhibitor | Probechem Biochemicals

You are here:Home-Chemical Inhibitors & Agonists-Metabolic Enzyme/Protease-Gutathione S-transferase (GST)-ML175

Chemical Structure : ML175

ML175 (ML-175)

Catalog No.: PC-25452Not For Human Use, Lab Use Only.

ML175 is a highly potent and selective inhibitor of glutathione S-tranferase omega (GSTO1) with IC50 of 28 nM.

Packing	Price	Stock	Quantity
50 mg		Get quote
100 mg		Get quote
250 mg		Get quote

Get Quotation Now

* Please select Quantity before adding items.

or Bulk Inquiry

Bulk size, bulk discount!

Welcome credit card payment!

E-mail: sales@probechem.com

Tech Support: tech@probechem.com

Purity & Documentation Purity: >98% (HPLC)

Biological Activity

ML175 is a highly potent and selective inhibitor of glutathione S-tranferase omega (GSTO1) with IC50 of 28 nM.
ML175 shows 350-fold selectivity against potential anti-targets as assessed by competitive ABPP profiling.
ML175 is active in situ, completely inhibiting GSTO1 at 250 nM compound concentration.
ML175 covalently labels the active site cysteine nucleophile of GSTO1.

Physicochemical Properties

M.Wt	367.71
Formula	C13H13ClF3N3O4
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	N-(3-(2-chloro-N-(4-nitrophenyl)acetamido)propyl)-2,2,2-trifluoroacetamide

References

1. Tsuboi K, et al. 2010 Aug 31 [updated 2011 Dec 12]. In: Probe Reports from the NIH Molecular Libraries Program [Internet].

Overnight Delivery
Fast & Safe Delivery Worldwide
Rewards Program

About Us

Our Services

Site Map

Join with Us
Product Use Citations

Pharmacological Glossary Abbreviations

Abbreviations

Quality Manual

Inquiry Form
How to Order

Terms & Conditions

Credit Card Payment

Shipping Rates & Policies

Privacy Policy
sales@probechem.com

ML175 (ML-175)

Biological Activity

Physicochemical Properties

References

Bulk Inquiry

* Indicates a Required FieldYour information is safe with us.

Get Quote

* Indicates a Required FieldYour information is safe with us.