Catalog No.: PC-38533Not For Human Use, Lab Use Only.
ML226 is a potent, selective, covalent inhibitor of α/β hydrolase domain-containing protein 11 (ABHD11) with IC50 values of 15 and 0.68 nM in vitro and in situ, respectively.
ML226 is a potent, selective, covalent inhibitor of α/β hydrolase domain-containing protein 11 (ABHD11) with IC50 values of 15 and 0.68 nM in vitro and in situ, respectively.
ML226 is 100-fold selective for ABHD11 over approximately 20 other serine hydrolases.
ML226 covalently carbamoylates the active site serine of ABHD11.
