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Chemical Structure : ML 278
Catalog No.: PC-62104Not For Human Use, Lab Use Only.
ML278 is a potent and reversible inhibitor of lipid uptake via SR-BI (scavenger receptor BI) with IC50 of 6 nM.
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ML278 is a potent and reversible inhibitor of lipid uptake via SR-BI (scavenger receptor BI) with IC50 of 6 nM.
ML278 is a plasma-stable, noncytotoxic probe that exhibits moderate metabolic stability, thus displaying improved properties for in vitro and in vivo studies.
ML278 increases the binding of HDL to SR-BI.
| M.Wt | 453.513 | |
| Formula | C23H23N3O5S | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Dockendorff C, et al. ACS Med Chem Lett. 2015 Feb 2;6(4):375-380.
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