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Chemical Structure : ML 279
Catalog No.: PC-62105Not For Human Use, Lab Use Only.
ML279 is a potent and reversible inhibitor of lipid uptake via SR-BI (scavenger receptor BI) with IC50 of 17 nM.
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ML279 is a potent and reversible inhibitor of lipid uptake via SR-BI (scavenger receptor BI) with IC50 of 17 nM.
ML279 stabilizes the interaction of HDL particles with SR-BI, and is non-toxic, plasma stable, and has improved solubility over alternative probe ML278.
| M.Wt | 468.55 | |
| Formula | C24H32N6O4 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Dockendorff C, et al. Bioorg Med Chem Lett. 2015 Jun 15;25(12):2594-8.
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