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Chemical Structure : ML298
CAS No.: 1426916-02-0
Catalog No.: PC-62137Not For Human Use, Lab Use Only.
ML298 is a potent, selective phospholipase PLD2 inhibitor with IC50 of 355 nM, displays >53-fold selectivity over PLD1 (IC50>20 uM).
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 10 mg | $128 | In stock | |
| 25 mg | $218 | In stock | |
| 50 mg | $368 | In stock | |
| 100 mg | Get quote |
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ML298 is a potent, selective phospholipase PLD2 inhibitor with IC50 of 355 nM, displays >53-fold selectivity over PLD1 (IC50>20 uM).
ML298 decreases invasive migration in U87-MG glioblastoma cells; has an attractive DMPK profile.
ML298 is an attractive tool compound to further dissect PLD2 function in multiple cellular and in vivo environments.
| M.Wt | 432.44 | |
| Formula | C22H23F3N4O2 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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| Chemical Name/SMILES |
3,4-difluoro-N-[2-[1-(3-fluorophenyl)-4-oxo-1,3,8-triazaspiro[4.5]dec-8-yl]ethyl]-benzamide |
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1. O'Reilly MC, et al. J Med Chem. 2013 Mar 28;56(6):2695-9.
2. Scott SA, et al. Probe Reports from the NIH Molecular Libraries Program [Internet].
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