Chemical Structure : ML303
CAS No.: 1638211-04-7
Catalog No.: PC-38457Not For Human Use, Lab Use Only.
ML303 is a potent, specific influenza virus non structural 1 (NS1) antagonist, shows potent reduction of viral titer in MDCK cells infected with the Influenza A/PR/8/34 strain with IC90 of 155 nM.
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ML303 is a potent, specific influenza virus non structural 1 (NS1) antagonist, shows potent reduction of viral titer in MDCK cells infected with the Influenza A/PR/8/34 strain with IC90 of 155 nM.
ML303 specifically restored the NS1-inhibited expression of the interferon mRNA, inhibited the NS1 function in mechanistic assay and exhibited a potent antiviral activity in culture.
M.Wt | 399.373 | |
Formula | C21H16F3N3O2 | |
Appearance | Solid | |
Storage |
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Solubility |
10 mM in DMSO |
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Chemical Name/SMILES |
2-methoxy-4-(3-methyl-1-(4-(trifluoromethyl)phenyl)-1H-pyrazolo[3,4-b]pyridin-4-yl)phenol |
1. Samarjit Patnaik, et al. Bethesda (MD): National Center for Biotechnology Information (US); 2010–.
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