Chemical Structure : ML328
CAS No.: 634175-34-1
Catalog No.: PC-20570Not For Human Use, Lab Use Only.
ML328 is a first-in-class, dual inhibitor of bacterial AddAB and RecBCD helicase-nucleases with IC50 of 15.7 and 4.8 uM, respectively.
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ML328 is a first-in-class, dual inhibitor of bacterial AddAB and RecBCD helicase-nucleases with IC50 of 15.7 and 4.8 uM, respectively.
M.Wt | 506.50 | |
Formula | C22H21F3N6O3S | |
Appearance | Solid | |
Storage |
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Solubility |
10 mM in DMSO |
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Chemical Name/SMILES |
8-ethyl-5-oxo-2-[4-[[3-(trifluoromethyl)phenyl]carbamothioyl]piperazin-1-yl]pyrido[2,3-d]pyrimidine-6-carboxylic acid |
1. TD Bannister, et al. Probe Reports from the NIH Molecular Libraries Program [Internet]. 2012
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