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ML328

Chemical Structure : ML328

CAS No.: 634175-34-1

ML328 (ML 328)

Catalog No.: PC-20570Not For Human Use, Lab Use Only.

ML328 is a first-in-class, dual inhibitor of bacterial AddAB and RecBCD helicase-nucleases with IC50 of 15.7 and 4.8 uM, respectively.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

ML328 is a first-in-class, dual inhibitor of bacterial AddAB and RecBCD helicase-nucleases with IC50 of 15.7 and 4.8 uM, respectively.

Physicochemical Properties

M.Wt 506.50
Formula C22H21F3N6O3S
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

8-ethyl-5-oxo-2-[4-[[3-(trifluoromethyl)phenyl]carbamothioyl]piperazin-1-yl]pyrido[2,3-d]pyrimidine-6-carboxylic acid

References

1. TD Bannister, et al. Probe Reports from the NIH Molecular Libraries Program [Internet]. 2012

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