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ML329

Chemical Structure : ML329

CAS No.: 19992-50-8

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ML329 (ML-329;ML 329)

Catalog No.: PC-42394Not For Human Use, Lab Use Only.

ML329 is a small molecule micropthalmia-associated transcription factor (MITF) that inhibits the promoter activity of a MITF target gene, melastatin (TRPM-1) with IC50 of 1.2 uM.

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5 mg $128 In stock
10 mg $198 In stock
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50 mg $548 In stock
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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

ML329 is a small molecule micropthalmia-associated transcription factor (MITF) that inhibits the promoter activity of a MITF target gene, melastatin (TRPM-1) with IC50 of 1.2 uM.
ML329 shows specific activity against the MITF-dependent cells, primary melanocytes but no effect on the viability in A375 cells.

Physicochemical Properties

M.Wt 328.34248
Formula C16H12N2O4S
Appearance Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility

DMSO: ≥ 31 mg/mL

Chemical Name/SMILES

Benzenesulfonamide, 4-[(1,4-dihydro-1,4-dioxo-2-naphthalenyl)amino]-

References

1. Faloon PW, et al. Probe Reports from the NIH Molecular Libraries Program [Internet].

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