You are here:Home-Chemical Inhibitors & Agonists-Membrane Transporter/Ion Channel-Potassium Channel-ML335
ML335

Chemical Structure : ML335

CAS No.: 825658-06-8

ML335 (ML 335;ML-335)

Catalog No.: PC-60337Not For Human Use, Lab Use Only.

ML335 (ML 335) is anovel potent, selective K2P2.1 (TREK-1) and K2P10.1 (TREK-2) channels activator with EC50 of 14.3 and 5.2 uM, respectively.

Packing Price Stock Quantity
10 mg $98 In stock
25 mg $158 In stock
50 mg $248 In stock
100 mg Get quote

Bulk size, bulk discount!

E-mail: sales@probechem.com

Tech Support: tech@probechem.com

Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

ML335 (ML 335) is anovel potent, selective K2P2.1 (TREK-1) and K2P10.1 (TREK-2) channels activator with EC50 of 14.3 and 5.2 uM, respectively.
ML335 displays no significant activity for K2P4.1 (at 50 uM); shows insensitivity to mutant K2P2.1(K271Q) , and has similar EC50 for K2P4.1(Q258K) (EC50=16.7 uM).

Physicochemical Properties

M.Wt 373.248
Formula C15H14Cl2N2O3S
Appearance Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

N-[(2,4-dichlorophenyl) methyl]-4-(methanesulfonamido) benzamide

References

1. Lolicato M, et al. Nature. 2017 Jul 20;547(7663):364-368.

Copyright © 2022 probechem.com. All Rights Reserved. probechem Copyright

Contact Us sales@probechem.com

Bulk Inquiry

* Indicates a Required FieldYour information is safe with us.

  • *Product name:
  • *Applicant name:
  • *Email address:
  • *Organization name:
  • *Requested quantity:
  • *Country:
  • *Additional Information:

Get Quote

* Indicates a Required FieldYour information is safe with us.

  • *Product name:
  • *Applicant name:
  • *Email address:
  • *Organization name:
  • *Requested quantity:
  • *Country:
  • Additional Information: