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Chemical Structure : ML335
CAS No.: 825658-06-8
Catalog No.: PC-60337Not For Human Use, Lab Use Only.
ML-335 (ML335) is a novel potent, selective K2P2.1 (TREK-1) and K2P10.1 (TREK-2) channels activator with EC50 of 14.3 and 5.2 uM, respectively.
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 10 mg | $98 | In stock | |
| 25 mg | $158 | In stock | |
| 50 mg | $248 | In stock | |
| 100 mg | Get quote |
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ML-335 (ML335) is anovel potent, selective K2P2.1 (TREK-1) and K2P10.1 (TREK-2) channels activator with EC50 of 14.3 and 5.2 uM, respectively.
ML335 displays no significant activity for K2P4.1 (at 50 uM); shows insensitivity to mutant K2P2.1(K271Q) , and has similar EC50 for K2P4.1(Q258K) (EC50=16.7 uM).
| M.Wt | 373.248 | |
| Formula | C15H14Cl2N2O3S | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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| Chemical Name/SMILES |
N-[(2,4-dichlorophenyl) methyl]-4-(methanesulfonamido) benzamide |
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1. Lolicato M, et al. Nature. 2017 Jul 20;547(7663):364-368.
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