Catalog No.: PC-42995Not For Human Use, Lab Use Only.
ML365 is a potent and selective inhibitor of KCNK3/TASK1 potassium channel, blocks TASK1 channels in both the thallium influx fluorescent assay (IC50=4 nM) and an automated electrophysiology assay (IC50=16 nM).
ML365 is a potent and selective inhibitor of KCNK3/TASK1 potassium channel, blocks TASK1 channels in both the thallium influx fluorescent assay (IC50=4 nM) and an automated electrophysiology assay (IC50=16 nM).
ML365 displays 98-fold selectivity over TASK1 (KCNK9), >7,500-fold over Kir2.1, KCNQ2 and hERG in thallium influx fluorescent assay.
ML365 is a useful pharmacological probe for in vitro studies of TASK1 function.
