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Chemical Structure : ML378
Catalog No.: PC-62332Not For Human Use, Lab Use Only.
ML378 (CID71710938, JJH-254) is an in vivo active carbamate-based dual inhibitor of lysophospholipase LYPLA1 (APT1) and LYPLA2 (APT2) with IC50 of 122 nM and 245 nM, repectively.
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ML378 (CID71710938, JJH-254) is an in vivo active carbamate-based dual inhibitor of lysophospholipase LYPLA1 (APT1) and LYPLA2 (APT2) with IC50 of 122 nM and 245 nM, repectively.
ML378 also inhibits ABHD6 with IC50 of 3.15 nM, and displays 13-fold and >40-fold selectivity over FAAH and 20SHs respectively.
| M.Wt | 534.01 | |
| Formula | C25H32ClN5O6 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Hulce JJ, et al. Probe Reports from the NIH Molecular Libraries Program [Internet].
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