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ML401

Chemical Structure : ML401

CAS No.: 1597489-14-9

ML401 (CID73169083, ML-401)

Catalog No.: PC-62127Not For Human Use, Lab Use Only.

ML401 (CID73169083) is a potent, functional antagonist of EBI-2 (Epstein-Barr virus-induced gene 2, GPR183) with IC50 of 1 nM, displays activity in a chemotaxis assay (IC50=6 nM).

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Biological Activity

ML401 (CID73169083) is a potent, functional antagonist of EBI-2 (Epstein-Barr virus-induced gene 2, GPR183) with IC50 of 1 nM, displays activity in a chemotaxis assay (IC50=6 nM).
ML401 exhibits a clean profile in a Eurofins/Ricerca panel as well as excellent rodent pharmacokinetics.
ML401 is a valuable tool to explore the in vivo effects of EBI-2 inhibition.

Physicochemical Properties

M.Wt 419.747
Formula C20H20BrClN2O
Appearance Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

(E)-3-(4-bromophenyl)-1-(4-(4-chlorobenzyl)-piperazin-1-yl)prop-2-en-1-one

References

1. Ardecky R, et al. Probe Reports from the NIH Molecular Libraries Program [Internet].

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