Chemical Structure : ML401
CAS No.: 1597489-14-9
Catalog No.: PC-62127Not For Human Use, Lab Use Only.
ML401 (CID73169083) is a potent, functional antagonist of EBI-2 (Epstein-Barr virus-induced gene 2, GPR183) with IC50 of 1 nM, displays activity in a chemotaxis assay (IC50=6 nM).
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ML401 (CID73169083) is a potent, functional antagonist of EBI-2 (Epstein-Barr virus-induced gene 2, GPR183) with IC50 of 1 nM, displays activity in a chemotaxis assay (IC50=6 nM).
ML401 exhibits a clean profile in a Eurofins/Ricerca panel as well as excellent rodent pharmacokinetics.
ML401 is a valuable tool to explore the in vivo effects of EBI-2 inhibition.
M.Wt | 419.747 | |
Formula | C20H20BrClN2O | |
Appearance | Solid | |
Storage |
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Solubility |
10 mM in DMSO |
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Chemical Name/SMILES |
(E)-3-(4-bromophenyl)-1-(4-(4-chlorobenzyl)-piperazin-1-yl)prop-2-en-1-one |
1. Ardecky R, et al. Probe Reports from the NIH Molecular Libraries Program [Internet].
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