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Chemical Structure : ML402
CAS No.: 298684-44-3
Catalog No.: PC-60336Not For Human Use, Lab Use Only.
ML402 is a potent, selective K2P2.1 (TREK-1) and K2P10.1 (TREK-2) channels activator with EC50 of 13.7 and 5.9 uM, respectively.
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 5 mg | $88 | In stock | |
| 10 mg | $128 | In stock | |
| 25 mg | $198 | In stock | |
| 50 mg | $328 | In stock | |
| 100 mg | Get quote |
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ML402 is a potent, selective K2P2.1 (TREK-1) and K2P10.1 (TREK-2) channels activator with EC50 of 13.7 and 5.9 uM, respectively.
ML402 displays no significant activity for K2P4.1 (at 50 uM); shows insensitivity to mutant K2P2.1(K271Q), and has similar EC50 for K2P4.1(Q258K) (EC50=13.6 uM).
| M.Wt | 295.781 | |
| Formula | C14H14ClNO2S | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
|
| Chemical Name/SMILES |
N-[2-(4-chloro-2-methylphenoxy)ethyl]thiophene-2-carboxamide |
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1. Lolicato M, et al. Nature. 2017 Jul 20;547(7663):364-368.
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