Chemical Structure : ML406
Catalog No.: PC-62126Not For Human Use, Lab Use Only.
ML406 is a small molecule Mtb bioA (DAPA synthase) enzyme inhibitor (IC50=30 nM) that shows anti-tubercular activity, dispalys >100-fold selectivity over bioD.
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ML406 is a small molecule Mtb bioA (DAPA synthase) enzyme inhibitor (IC50=30 nM) that shows anti-tubercular activity, dispalys >100-fold selectivity over bioD; exhibits WT M. tb (H37Rv) growth inhibition without biotin with an IC50 of 3.2 uM.
M.Wt | 352.39 | |
Formula | C20H20N2O4 | |
Appearance | Solid | |
Storage |
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Solubility |
10 mM in DMSO |
1. Casalena D, et al. Probe Reports from the NIH Molecular Libraries Program [Internet].
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