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Chemical Structure : MLE4901
CAS No.: 941690-55-7
Catalog No.: PC-61237Not For Human Use, Lab Use Only.
Pavinetant (MLE4901, AZD-2624) is a potent, selective, orally active neurokinin 3 (NK3R) antagonist for the treatment of menopausal hot flushes.
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 5 mg | $198 | In stock | |
| 10 mg | $298 | In stock | |
| 25 mg | $498 | In stock | |
| 50 mg | Get quote | ||
| 100 mg | Get quote |
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Pavinetant (MLE4901, AZD-2624) is a potent, selective, orally active neurokinin 3 (NK3R) receptor antagonist for the treatment of menopausal hot flushes.
Pavinetant (MLE4901, AZD-2624) demonstrates drug-like properties with low metabolic turnover rate in vitro and moderate human plasma protein binding.
| M.Wt | 459.56 | |
| Formula | C26H25N3O3S | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
|
| Chemical Name/SMILES |
(S)-3-(methylsulfonamido)-2-phenyl-N-(1-phenylpropyl)quinoline-4-carboxamide |
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1. Li Y, et al. Xenobiotica. 2010 Nov;40(11):721-9.
2. Skorupskaite K, et al. Neuroendocrinology. 2017 Apr 5. doi: 10.1159/000473893.
3. Prague JK, et al. Lancet. 2017 May 6;389(10081):1809-1820.
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