Chemical Structure : MLE4901
CAS No.:
941690-55-7
MLE4901
(Pavinetant, MLE-4901, AZD-2624, AZD2624)
Catalog No. : PC-61237Not For Human Use, Lab Use Only.
Pavinetant (MLE4901, AZD-2624) is a potent, selective, orally active neurokinin 3 (NK3R) antagonist for the treatment of menopausal hot flushes.
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Purity & Documentation Purity:
>98% (HPLC) Select Batch: PC-6123701
Biological Activity
Pavinetant (MLE4901, AZD-2624) is a potent, selective, orally active neurokinin 3 (NK3R) receptor antagonist for the treatment of menopausal hot flushes.
Physicochemical Properties
M.Wt
459.56
Formula
C26H25N3O3S
Appearance
Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility
10 mM in DMSO
Chemical Name/SMILES
(S)-3-(methylsulfonamido)-2-phenyl-N-(1-phenylpropyl)quinoline-4-carboxamide
References
1. Li Y, et al. Xenobiotica
2. Skorupskaite K, et al. Neuroendocrinology
3. Prague JK, et al. Lancet.
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