Welcome to ProbeChem!Global Supplier of Chemical Probes, Inhibitors & Agonists.

You are here:Home-Chemical Inhibitors & Agonists-Ras-Raf-MAPK-ERK Pathway-Mixed Lineage Kinase (MLK)-MLK3 inhibitor 37
MLK3 inhibitor 37

Chemical Structure : MLK3 inhibitor 37

CAS No.:

MLK3 inhibitor 37

Catalog No.: PC-23623Not For Human Use, Lab Use Only.

MLK3 inhibitor 37 is a potent, selective mixed-lineage protein kinase 3 (MLK3, MAP3K11)inhibitor with IC50 of <1 nM, exhibiting kinome-wide selectivity.

Packing Price Stock Quantity
50 mg Get quote
100 mg Get quote
250 mg Get quote

Bulk size, bulk discount!

E-mail: sales@probechem.com

Tech Support: tech@probechem.com

Purity & Documentation Purity: >98% (HPLC)

Biological Activity

MLK3 inhibitor 37 is a potent, selective mixed-lineage protein kinase 3 (MLK3, MAP3K11)inhibitor with IC50 of <1 nM, exhibiting kinome-wide selectivity.

Physicochemical Properties

M.Wt 490.42
Formula C20H16F6N4O2S
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

N4-[3-(Methylsulfonyl)benzyl]-5-(trifluoromethyl)-N2-[4-(trifluoromethyl)phenyl]pyrimidine-2,4-diamine

References

1. Sander P, et al. J Med Chem. 2024 Dec 16. doi: 10.1021/acs.jmedchem.4c02552.

Copyright © 2022 probechem.com. All Rights Reserved. probechem Copyright

Contact Us sales@probechem.com

Bulk Inquiry

* Indicates a Required FieldYour information is safe with us.

  • *Product name:
  • *Applicant name:
  • *Email address:
  • *Organization name:
  • *Requested quantity:
  • *Country:
  • *Additional Information:

Get Quote

* Indicates a Required FieldYour information is safe with us.

  • *Product name:
  • *Applicant name:
  • *Email address:
  • *Organization name:
  • *Requested quantity:
  • *Country:
  • Additional Information: