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Chemical Structure : MLS000532223
CAS No.: 16616-39-0
Catalog No.: PC-61468Not For Human Use, Lab Use Only.
MLS000532223 is a high affinity, selective inhibitor of Rho family GTPases with EC50 of 16-120 uM.
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 5 mg | $248 | In stock | |
| 10 mg | $388 | In stock | |
| 25 mg | $588 | In stock | |
| 50 mg | Get quote | ||
| 100 mg | Get quote |
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MLS000532223 is a high affinity, selective inhibitor of Rho family GTPases with EC50 of 16-120 uM.
MLS000532223 prevents GTP binding to several GTPases in a dose-dependent manner and is active in biochemical and cell-based secondary assays.
MLS000532223 inhibits actin rearrangements and changes in cell morphology, inhibits IgE induced morphological changes in mast cells; inhibits ligand-stimulated β-hexosaminidase secretion of RBL cells.
| M.Wt | 251.241 | |
| Formula | C15H9NO3 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
|
| Chemical Name/SMILES |
1-(3-nitrophenyl)-3-phenylprop-2-yn-1-one |
|
1. Surviladze Z, et al. J Biomol Screen. 2010 Jan;15(1):10-20.
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