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MMAD hydrochloride

Chemical Structure : MMAD hydrochloride

CAS No.: 173441-26-4

MMAD hydrochloride (Demethyldolastatin 10 hydrochloride;Monomethylauristatin D hydrochloride;Monomethyl Dolastatin 10 hydrochloride)

Catalog No.: PC-45998Not For Human Use, Lab Use Only.

A potent tubulin inhibitor that is a toxin payload in antibody drug conjugates (ADCs)..

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50 mg $1550.4 In stock
100 mg $2584 In stock

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

A potent tubulin inhibitor that is a toxin payload in antibody drug conjugates (ADCs).

Physicochemical Properties

M.Wt 807.5253
Formula C41H67ClN6O6S
Appearance Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

L-Valinamide, N-methyl-L-valyl-N-[(1S,2R)-2-methoxy-4-[(2S)-2-[(1R,2R)-1-methoxy-2-methyl-3-oxo-3-[[(1S)-2-phenyl-1-(2-thiazolyl)ethyl]amino]propyl]-1-pyrrolidinyl]-1-[(1S)-1-methylpropyl]-4-oxobutyl]-N-methyl-, hydrochloride (1:1)

References

1. Chudasama V, et al. Nat Chem. 2016 Feb;8(2):114-9.

2. Leal M, et al. Bioconjug Chem. 2015 Nov 18;26(11):2223-32.

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