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Chemical Structure : MMH1
Catalog No.: PC-22822Not For Human Use, Lab Use Only.
MMH1 is a potent, selective, covalent JQ1-derived PROTAC degrader of BRD4 via DCAF16 (BRD4BD2, DC50=1 nM), functions as a molecular glue to recruit DCAF16 selectively to BRD4 BD2, causing degradation of BRD4.
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MMH1 is a potent, selective, covalent JQ1-derived PROTAC degrader of BRD4 via DCAF16 (BRD4BD2, DC50=1 nM, Dmax=95%), functions as a molecular glue to recruit DCAF16 selectively to BRD4 BD2, causing degradation of BRD4.
| M.Wt | 491.61 | |
| Formula | C26H29N5O3S | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Li YD, et al. Nat Chem Biol. 2024 Jul 29. doi: 10.1038/s41589-024-01668-4.
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